Welcome to the Antimicrobial Stewardship (AMS) Hub
This tool synthesizes global AMS guidelines (WHO AWaRe, CDC, ICMR, NICE) into actionable, role-based insights. Select your role to see relevant principles and actions, or use the tools to support clinical decisions.
Hackathon Demo Mode
This app is running in demo mode. The **"Phase 1"** tab contains functional, rule-based tools. The **"Phase 2"** tab provides a *simulated* demo of the future AI co-pilot, perfect for your presentation.
Select Your Role
Doctor / Prescriber
Get guidelines for diagnosis, empiric therapy, de-escalation, and documentation.
Pharmacist
Focus on formulary management, dose optimization, IV-to-PO conversion, and audits.
Microbiologist
Guidelines on specimen collection, rapid diagnostics, antibiogram creation, and selective reporting.
Nurse
Best practices for timely administration, monitoring for adverse effects, and patient education.
AMS Lead / Committee
Actions for program implementation, leadership engagement, policy creation, and reporting.
Administrator
Ensuring accountability, allocating resources, and integrating AMS with quality improvement goals.
Stewardship Tools
Antibiotic Calculator
Get evidence-based empiric therapy recommendations based on clinical scenario and patient factors.
Surgical Prophylaxis
Check standard antibiotic prophylaxis guidelines for common surgical procedures.
IV-to-PO Switch Guide
Review clinical criteria for switching to oral therapy and see common drug conversions.
Demo Antibiogram
View a sample hospital antibiogram to understand local resistance patterns.
Guideline Library
Access direct links to the source guidelines from WHO, CDC, ICMR, NICE, and more.
Antibiotic Therapy Calculator
Provides *example* recommendations based on synthesized guidelines. **Not a substitute for clinical judgment.**
Patient Data (Optional)
Allergies & Risk Factors
Calculated Patient Data
Primary Recommendation
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Secondary Recommendation
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Rationale
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Recommended Duration
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Stewardship Review Plan
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Clinical Warnings
Dosing & Adjustments
WHO AWaRe Classification
Surgical Prophylaxis (SCIP) Guide
Guideline-based recommendations for common procedures. Always confirm with local policy.
Primary Regimen
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Penicillin Allergy Alternative
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Timing & Dosing Notes
IV-to-PO (Oral) Switch Guide
A key stewardship intervention. Review clinical criteria and common conversions below.
Clinical Criteria for Switching
- Clinical improvement observed (e.g., resolution of fever, normalizing WBC).
- Hemodynamically stable (normal heart rate, blood pressure).
- Afebrile for > 24 hours.
- Able to tolerate oral intake (no NPO status, vomiting, or malabsorption issues).
- Specific infection does not require prolonged IV therapy (e.g., endocarditis, osteomyelitis, CNS infection).
- A suitable oral agent with high bioavailability is available.
Common IV-to-PO Conversions
| IV Agent | Oral Equivalent | Bioavailability |
|---|---|---|
| Levofloxacin | Levofloxacin | > 99% |
| Moxifloxacin | Moxifloxacin | ~ 90% |
| Doxycycline | Doxycycline | > 95% |
| Metronidazole | Metronidazole | > 99% |
| TMP-SMX | TMP-SMX | ~ 95% |
| Linezolid | Linezolid | 100% |
| Fluconazole | Fluconazole | > 90% |
| Ciprofloxacin | Ciprofloxacin | ~ 70-80% |
| Ampicillin | Amoxicillin | ~ 80-90% |
Demo Antibiogram - Sample Hospital (2023)
This is a *sample* antibiogram showing % Susceptible (S). Used to guide empiric therapy.
| Organism (Urine) | # | Amp/Sul | Cefazolin | Ceftriaxone | Cipro | Nitro | Pip/Tazo | TMP/SMX |
|---|---|---|---|---|---|---|---|---|
| E. coli | 452 | 68% | 82% | 85% | 70% | 96% | 92% | 74% |
| K. pneumoniae | 188 | 60% | 79% | 81% | 78% | N/A | 90% | 79% |
| P. mirabilis | 92 | 75% | 88% | 89% | 80% | R | 94% | 81% |
High Susceptibility (> 90%) - Good empiric choice.
Low Susceptibility (< 80%) - Poor empiric choice.
R: Intrinsic Resistance. N/A: Not Typically Tested.
Guideline Library
Direct links to the source guidelines and resources used in this application.
WHO AWaRe Classification (2023)
The 2023 WHO AWaRe classification of antibiotics for evaluation and monitoring of use.
CDC Core Elements of AMS
The US CDC's practical framework for implementing AMS programs in various settings.
ICMR AMS Guidelines (India)
Indian Council of Medical Research's hub for AMR and stewardship guidelines.
NICE (UK) Guideline [NG15]
The specific NICE guideline covering antimicrobial stewardship in health and social care.
IDSA/SHEA AMS Guideline
The joint IDSA and SHEA practice guideline on implementing AMS programs.
ESCMID AMS Topic Hub
European Society of Clinical Microbiology and Infectious Diseases topic page for AMS.
AMS AI Co-pilot (Simulated Demo)
This is a pre-scripted demo for your hackathon. Click the prompts below to see the simulated AI response.
Please click one of the demo prompts below to see how I can handle complex, natural language queries.
- "What are the empiric options for HAP in a patient with a severe penicillin allergy and an eGFR of 20?"
- "Summarize the latest IDSA guidelines on MRSA."
- "What is the standard duration for E. coli bacteremia?"
- "My patient has uncomplicated cystitis. What's the best oral option?"
- "Follow-up: My cystitis patient's culture came back as ESBL. They aren't improving. What now?"
About Phase 2
This AI Co-pilot demonstrates the power of Large Language Models (LLMs) in clinical decision support.
Natural Language Query
Understands complex, real-world clinical vignettes instead of simple dropdowns.
Local Data Analysis
Future versions will allow you to upload your local antibiogram for context-aware recommendations.
Real-Time DDI Checks
Can be integrated with EMRs to check for drug-drug interactions automatically.
Automated Reporting
Can analyze prescribing data and generate audit reports for the AMS committee.
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